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Industry analysts project retatrutide will launch in the $1,200$1,500 monthly range , slightly above current Mounjaro/Zepbound pricing

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This synthetic peptide (exendin-4 analog) retained the beneficial properties of the natural peptide while being manufactured for clinical use

While the semaglutide CVOTs did not show an increased incidence of hospitalization for HF compared to placebo (101), in earlier smaller studies with liraglutide in patients with HF with reduced left ventricular ejection fraction, the GLP-1RA was associated with increased incidence of serious cardiac events (rhythm disorders, worsening of HF) (102, 103)

Sammeturi M, Shaik AH, Bongu SBR, Cheemanapalli S, Mohammad A, Kodidhela LD